recombinant zebrafish vegf 165 protein Search Results


93
R&D Systems recombinant zebrafish vegf165
Analysis of regenerative angiogenesis and neurogenesis after <t>VEGF165</t> injection. (A) PCNA immunohistostaining (proliferating cells in purple) in telencephalon sections of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish (blood vessels in green) after microinjection with PBS (vehicle) and VEGF165 (50 µg/mL) at the SW injury site. Scale bars: 200 µm. (B–D) Quantification of different angiogenic parameters shows an increasing regenerative angiogenesis tendency in the SW hemisphere of VEGF165-injected zebrafish compared with the SW hemisphere of PBS-injected zebrafish at 1 dpl. (E) Quantification of the ventricular proliferative surface of fish injected with PBS and VEGF165 showing an increasing tendency for NSC proliferation. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. * P < 0.05, vs . the SW hemisphere of PBS-injected zebrafish. dpl: Day(s) post-lesion; EGFP: enhanced green fluorescent protein; GFP: green fluorescent protein; PBS: phosphate-buffered saline; PCNA: proliferating cell nuclear antigen; SW: stab-wounded; VEGF: vascular endothelial growth factor.
Recombinant Zebrafish Vegf165, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/recombinant+zebrafish+vegf+165+protein/Recombinant+Zebrafish+VEGF+165+Protein/pmc11826465-79-14-39
Average 93 stars, based on 1 article reviews
recombinant zebrafish vegf165 - by Bioz Stars, 2026-09
93/100 stars
  Buy from Supplier

93
R&D Systems vegf165
Analysis of regenerative angiogenesis and neurogenesis after <t>VEGF165</t> injection. (A) PCNA immunohistostaining (proliferating cells in purple) in telencephalon sections of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish (blood vessels in green) after microinjection with PBS (vehicle) and VEGF165 (50 µg/mL) at the SW injury site. Scale bars: 200 µm. (B–D) Quantification of different angiogenic parameters shows an increasing regenerative angiogenesis tendency in the SW hemisphere of VEGF165-injected zebrafish compared with the SW hemisphere of PBS-injected zebrafish at 1 dpl. (E) Quantification of the ventricular proliferative surface of fish injected with PBS and VEGF165 showing an increasing tendency for NSC proliferation. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. * P < 0.05, vs . the SW hemisphere of PBS-injected zebrafish. dpl: Day(s) post-lesion; EGFP: enhanced green fluorescent protein; GFP: green fluorescent protein; PBS: phosphate-buffered saline; PCNA: proliferating cell nuclear antigen; SW: stab-wounded; VEGF: vascular endothelial growth factor.
Vegf165, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/recombinant+zebrafish+vegf+165+protein/Recombinant+Zebrafish+VEGF+165+Protein%2C+CF/pmc11826465-79-33-39
Average 93 stars, based on 1 article reviews
vegf165 - by Bioz Stars, 2026-09
93/100 stars
  Buy from Supplier

90
R&D Systems recombinant zebrafish vegf a zvegf
Effect of TK receptor inhibitors on the angiogenic activity of FGF2 and VEGF‐A in zebrafish embryos
Recombinant Zebrafish Vegf A Zvegf, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/recombinant+zebrafish+vegf+165+protein/Recombinant+Zebrafish+VEGF+165+Protein%2C+CF/pmc06512384-52-0-9
Average 90 stars, based on 1 article reviews
recombinant zebrafish vegf a zvegf - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

90
R&D Systems zebrafish vegf a
Effect of TK receptor inhibitors on the angiogenic activity of FGF2 and VEGF‐A in zebrafish embryos
Zebrafish Vegf A, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/recombinant+zebrafish+vegf+165+protein/Recombinant+Zebrafish+VEGF+165+Protein/pmc04645220-131-0-4
Average 90 stars, based on 1 article reviews
zebrafish vegf a - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

N/A
The Recombinant Zebrafish VEGF 165 Protein from R D Systems is derived from Sf 21 stably transfected The Recombinant Zebrafish VEGF 165 Protein has been validated for the following applications Bioactivity
  Buy from Supplier

N/A
The Recombinant Zebrafish VEGF 165 Protein from R D Systems is derived from Sf 21 stably transfected The Recombinant Zebrafish VEGF 165 Protein has been validated for the following applications Bioactivity
  Buy from Supplier

Image Search Results


Analysis of regenerative angiogenesis and neurogenesis after VEGF165 injection. (A) PCNA immunohistostaining (proliferating cells in purple) in telencephalon sections of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish (blood vessels in green) after microinjection with PBS (vehicle) and VEGF165 (50 µg/mL) at the SW injury site. Scale bars: 200 µm. (B–D) Quantification of different angiogenic parameters shows an increasing regenerative angiogenesis tendency in the SW hemisphere of VEGF165-injected zebrafish compared with the SW hemisphere of PBS-injected zebrafish at 1 dpl. (E) Quantification of the ventricular proliferative surface of fish injected with PBS and VEGF165 showing an increasing tendency for NSC proliferation. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. * P < 0.05, vs . the SW hemisphere of PBS-injected zebrafish. dpl: Day(s) post-lesion; EGFP: enhanced green fluorescent protein; GFP: green fluorescent protein; PBS: phosphate-buffered saline; PCNA: proliferating cell nuclear antigen; SW: stab-wounded; VEGF: vascular endothelial growth factor.

Journal: Neural Regeneration Research

Article Title: Telencephalic stab wound injury induces regenerative angiogenesis and neurogenesis in zebrafish: unveiling the role of vascular endothelial growth factor signaling and microglia

doi: 10.4103/NRR.NRR-D-23-01881

Figure Lengend Snippet: Analysis of regenerative angiogenesis and neurogenesis after VEGF165 injection. (A) PCNA immunohistostaining (proliferating cells in purple) in telencephalon sections of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish (blood vessels in green) after microinjection with PBS (vehicle) and VEGF165 (50 µg/mL) at the SW injury site. Scale bars: 200 µm. (B–D) Quantification of different angiogenic parameters shows an increasing regenerative angiogenesis tendency in the SW hemisphere of VEGF165-injected zebrafish compared with the SW hemisphere of PBS-injected zebrafish at 1 dpl. (E) Quantification of the ventricular proliferative surface of fish injected with PBS and VEGF165 showing an increasing tendency for NSC proliferation. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. * P < 0.05, vs . the SW hemisphere of PBS-injected zebrafish. dpl: Day(s) post-lesion; EGFP: enhanced green fluorescent protein; GFP: green fluorescent protein; PBS: phosphate-buffered saline; PCNA: proliferating cell nuclear antigen; SW: stab-wounded; VEGF: vascular endothelial growth factor.

Article Snippet: The positive effects of VEGF on angiogenesis and brain regeneration were investigated by injecting recombinant zebrafish VEGF165 at the lesion site: the fish received an intraparenchymal microinjection with 1× PBS or 50 μg/mL VEGF165 in 1× PBS (REF: 1247-ZV/CF, R&D Systems, Noyal Châtillon sur Seiche, France).

Techniques: Injection, Microinjection, Saline

Microglial recruitment is regulated by Vegf signaling. The SW hemisphere was compared with the respective contralateral hemisphere at 3 dpl. (A, C) Telencephalon sections of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish (microglia in red). Scale bars: 200 µm. (B) Quantification of mpeg + cells showing a decrease in tivozanib-injected zebrafish compared with DMSO-injected zebrafish. (D) Quantification of mpeg + cells showing an increasing tendency in VEGF165-injected zebrafish compared with PBS-injected zebrafish. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. *** P < 0.001, vs . the contralateral hemisphere. DMSO: Dimethyl sulfoxide; dpl: day(s) post-lesion; mpeg: macrophage‐expressed gene; PBS: phosphate-buffered saline; SW: stab-wounded; Vegf/VEGF: vascular endothelial growth factor.

Journal: Neural Regeneration Research

Article Title: Telencephalic stab wound injury induces regenerative angiogenesis and neurogenesis in zebrafish: unveiling the role of vascular endothelial growth factor signaling and microglia

doi: 10.4103/NRR.NRR-D-23-01881

Figure Lengend Snippet: Microglial recruitment is regulated by Vegf signaling. The SW hemisphere was compared with the respective contralateral hemisphere at 3 dpl. (A, C) Telencephalon sections of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish (microglia in red). Scale bars: 200 µm. (B) Quantification of mpeg + cells showing a decrease in tivozanib-injected zebrafish compared with DMSO-injected zebrafish. (D) Quantification of mpeg + cells showing an increasing tendency in VEGF165-injected zebrafish compared with PBS-injected zebrafish. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. *** P < 0.001, vs . the contralateral hemisphere. DMSO: Dimethyl sulfoxide; dpl: day(s) post-lesion; mpeg: macrophage‐expressed gene; PBS: phosphate-buffered saline; SW: stab-wounded; Vegf/VEGF: vascular endothelial growth factor.

Article Snippet: The positive effects of VEGF on angiogenesis and brain regeneration were investigated by injecting recombinant zebrafish VEGF165 at the lesion site: the fish received an intraparenchymal microinjection with 1× PBS or 50 μg/mL VEGF165 in 1× PBS (REF: 1247-ZV/CF, R&D Systems, Noyal Châtillon sur Seiche, France).

Techniques: Injection, Saline

Microglial and endothelial cell proliferation following brain lesion and modulation of Vegf signaling. (A) Representative images of PCNA immunostaining of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish following microlesion/injection with DAPI counterstaining. (B) Higher magnification of the white panels in A illustrating endothelial cell proliferation (Fli + /PCNA + ) and microglial proliferation (mpeg + /PCNA + ). Scale bar: 120 µm (A) and 70 µm and magnified 7 µm (B). (C–E) Quantification of PCNA + , PCNA + /Fli + , and PCNA + /mpeg + cells in the SW hemisphere following phosphate-buffered saline (PBS) and VEGF165 microinjection. (F–H) Quantification of PCNA + , PCNA + /Fli + , and PCNA + /mpeg + cells in the SW hemisphere following DMSO and tivozanib microinjection. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. * P < 0.05, vs . the lesioned hemisphere of the respective control. DAPI: 4′,6-Diamidino-2-phenylindole; DMSO: dimethyl sulfoxide; EGFP: enhanced green fluorescent protein; mpeg: macrophage‐expressed gene; PBS: phosphate-buffered saline; PCNA: proliferating cell nuclear antigen; SW: stab-wounded; Vegf/VEGF: vascular endothelial growth factor.

Journal: Neural Regeneration Research

Article Title: Telencephalic stab wound injury induces regenerative angiogenesis and neurogenesis in zebrafish: unveiling the role of vascular endothelial growth factor signaling and microglia

doi: 10.4103/NRR.NRR-D-23-01881

Figure Lengend Snippet: Microglial and endothelial cell proliferation following brain lesion and modulation of Vegf signaling. (A) Representative images of PCNA immunostaining of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish following microlesion/injection with DAPI counterstaining. (B) Higher magnification of the white panels in A illustrating endothelial cell proliferation (Fli + /PCNA + ) and microglial proliferation (mpeg + /PCNA + ). Scale bar: 120 µm (A) and 70 µm and magnified 7 µm (B). (C–E) Quantification of PCNA + , PCNA + /Fli + , and PCNA + /mpeg + cells in the SW hemisphere following phosphate-buffered saline (PBS) and VEGF165 microinjection. (F–H) Quantification of PCNA + , PCNA + /Fli + , and PCNA + /mpeg + cells in the SW hemisphere following DMSO and tivozanib microinjection. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. * P < 0.05, vs . the lesioned hemisphere of the respective control. DAPI: 4′,6-Diamidino-2-phenylindole; DMSO: dimethyl sulfoxide; EGFP: enhanced green fluorescent protein; mpeg: macrophage‐expressed gene; PBS: phosphate-buffered saline; PCNA: proliferating cell nuclear antigen; SW: stab-wounded; Vegf/VEGF: vascular endothelial growth factor.

Article Snippet: The positive effects of VEGF on angiogenesis and brain regeneration were investigated by injecting recombinant zebrafish VEGF165 at the lesion site: the fish received an intraparenchymal microinjection with 1× PBS or 50 μg/mL VEGF165 in 1× PBS (REF: 1247-ZV/CF, R&D Systems, Noyal Châtillon sur Seiche, France).

Techniques: Immunostaining, Injection, Saline, Microinjection, Control

Analysis of regenerative angiogenesis and neurogenesis after VEGF165 injection. (A) PCNA immunohistostaining (proliferating cells in purple) in telencephalon sections of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish (blood vessels in green) after microinjection with PBS (vehicle) and VEGF165 (50 µg/mL) at the SW injury site. Scale bars: 200 µm. (B–D) Quantification of different angiogenic parameters shows an increasing regenerative angiogenesis tendency in the SW hemisphere of VEGF165-injected zebrafish compared with the SW hemisphere of PBS-injected zebrafish at 1 dpl. (E) Quantification of the ventricular proliferative surface of fish injected with PBS and VEGF165 showing an increasing tendency for NSC proliferation. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. * P < 0.05, vs . the SW hemisphere of PBS-injected zebrafish. dpl: Day(s) post-lesion; EGFP: enhanced green fluorescent protein; GFP: green fluorescent protein; PBS: phosphate-buffered saline; PCNA: proliferating cell nuclear antigen; SW: stab-wounded; VEGF: vascular endothelial growth factor.

Journal: Neural Regeneration Research

Article Title: Telencephalic stab wound injury induces regenerative angiogenesis and neurogenesis in zebrafish: unveiling the role of vascular endothelial growth factor signaling and microglia

doi: 10.4103/NRR.NRR-D-23-01881

Figure Lengend Snippet: Analysis of regenerative angiogenesis and neurogenesis after VEGF165 injection. (A) PCNA immunohistostaining (proliferating cells in purple) in telencephalon sections of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish (blood vessels in green) after microinjection with PBS (vehicle) and VEGF165 (50 µg/mL) at the SW injury site. Scale bars: 200 µm. (B–D) Quantification of different angiogenic parameters shows an increasing regenerative angiogenesis tendency in the SW hemisphere of VEGF165-injected zebrafish compared with the SW hemisphere of PBS-injected zebrafish at 1 dpl. (E) Quantification of the ventricular proliferative surface of fish injected with PBS and VEGF165 showing an increasing tendency for NSC proliferation. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. * P < 0.05, vs . the SW hemisphere of PBS-injected zebrafish. dpl: Day(s) post-lesion; EGFP: enhanced green fluorescent protein; GFP: green fluorescent protein; PBS: phosphate-buffered saline; PCNA: proliferating cell nuclear antigen; SW: stab-wounded; VEGF: vascular endothelial growth factor.

Article Snippet: The positive effects of VEGF on angiogenesis and brain regeneration were investigated by injecting recombinant zebrafish VEGF165 at the lesion site: the fish received an intraparenchymal microinjection with 1× PBS or 50 μg/mL VEGF165 in 1× PBS (REF: 1247-ZV/CF, R&D Systems, Noyal Châtillon sur Seiche, France).

Techniques: Injection, Microinjection, Saline

Microglial recruitment is regulated by Vegf signaling. The SW hemisphere was compared with the respective contralateral hemisphere at 3 dpl. (A, C) Telencephalon sections of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish (microglia in red). Scale bars: 200 µm. (B) Quantification of mpeg + cells showing a decrease in tivozanib-injected zebrafish compared with DMSO-injected zebrafish. (D) Quantification of mpeg + cells showing an increasing tendency in VEGF165-injected zebrafish compared with PBS-injected zebrafish. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. *** P < 0.001, vs . the contralateral hemisphere. DMSO: Dimethyl sulfoxide; dpl: day(s) post-lesion; mpeg: macrophage‐expressed gene; PBS: phosphate-buffered saline; SW: stab-wounded; Vegf/VEGF: vascular endothelial growth factor.

Journal: Neural Regeneration Research

Article Title: Telencephalic stab wound injury induces regenerative angiogenesis and neurogenesis in zebrafish: unveiling the role of vascular endothelial growth factor signaling and microglia

doi: 10.4103/NRR.NRR-D-23-01881

Figure Lengend Snippet: Microglial recruitment is regulated by Vegf signaling. The SW hemisphere was compared with the respective contralateral hemisphere at 3 dpl. (A, C) Telencephalon sections of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish (microglia in red). Scale bars: 200 µm. (B) Quantification of mpeg + cells showing a decrease in tivozanib-injected zebrafish compared with DMSO-injected zebrafish. (D) Quantification of mpeg + cells showing an increasing tendency in VEGF165-injected zebrafish compared with PBS-injected zebrafish. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. *** P < 0.001, vs . the contralateral hemisphere. DMSO: Dimethyl sulfoxide; dpl: day(s) post-lesion; mpeg: macrophage‐expressed gene; PBS: phosphate-buffered saline; SW: stab-wounded; Vegf/VEGF: vascular endothelial growth factor.

Article Snippet: The positive effects of VEGF on angiogenesis and brain regeneration were investigated by injecting recombinant zebrafish VEGF165 at the lesion site: the fish received an intraparenchymal microinjection with 1× PBS or 50 μg/mL VEGF165 in 1× PBS (REF: 1247-ZV/CF, R&D Systems, Noyal Châtillon sur Seiche, France).

Techniques: Injection, Saline

Microglial and endothelial cell proliferation following brain lesion and modulation of Vegf signaling. (A) Representative images of PCNA immunostaining of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish following microlesion/injection with DAPI counterstaining. (B) Higher magnification of the white panels in A illustrating endothelial cell proliferation (Fli + /PCNA + ) and microglial proliferation (mpeg + /PCNA + ). Scale bar: 120 µm (A) and 70 µm and magnified 7 µm (B). (C–E) Quantification of PCNA + , PCNA + /Fli + , and PCNA + /mpeg + cells in the SW hemisphere following phosphate-buffered saline (PBS) and VEGF165 microinjection. (F–H) Quantification of PCNA + , PCNA + /Fli + , and PCNA + /mpeg + cells in the SW hemisphere following DMSO and tivozanib microinjection. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. * P < 0.05, vs . the lesioned hemisphere of the respective control. DAPI: 4′,6-Diamidino-2-phenylindole; DMSO: dimethyl sulfoxide; EGFP: enhanced green fluorescent protein; mpeg: macrophage‐expressed gene; PBS: phosphate-buffered saline; PCNA: proliferating cell nuclear antigen; SW: stab-wounded; Vegf/VEGF: vascular endothelial growth factor.

Journal: Neural Regeneration Research

Article Title: Telencephalic stab wound injury induces regenerative angiogenesis and neurogenesis in zebrafish: unveiling the role of vascular endothelial growth factor signaling and microglia

doi: 10.4103/NRR.NRR-D-23-01881

Figure Lengend Snippet: Microglial and endothelial cell proliferation following brain lesion and modulation of Vegf signaling. (A) Representative images of PCNA immunostaining of Tg( fli:EGFP × mpeg1.1:mCherry ) zebrafish following microlesion/injection with DAPI counterstaining. (B) Higher magnification of the white panels in A illustrating endothelial cell proliferation (Fli + /PCNA + ) and microglial proliferation (mpeg + /PCNA + ). Scale bar: 120 µm (A) and 70 µm and magnified 7 µm (B). (C–E) Quantification of PCNA + , PCNA + /Fli + , and PCNA + /mpeg + cells in the SW hemisphere following phosphate-buffered saline (PBS) and VEGF165 microinjection. (F–H) Quantification of PCNA + , PCNA + /Fli + , and PCNA + /mpeg + cells in the SW hemisphere following DMSO and tivozanib microinjection. The data are presented as the mean ± standard error of the mean ( n = 5–6 per condition from two independent experiments) and were analyzed with Student’s t -test. * P < 0.05, vs . the lesioned hemisphere of the respective control. DAPI: 4′,6-Diamidino-2-phenylindole; DMSO: dimethyl sulfoxide; EGFP: enhanced green fluorescent protein; mpeg: macrophage‐expressed gene; PBS: phosphate-buffered saline; PCNA: proliferating cell nuclear antigen; SW: stab-wounded; Vegf/VEGF: vascular endothelial growth factor.

Article Snippet: The positive effects of VEGF on angiogenesis and brain regeneration were investigated by injecting recombinant zebrafish VEGF165 at the lesion site: the fish received an intraparenchymal microinjection with 1× PBS or 50 μg/mL VEGF165 in 1× PBS (REF: 1247-ZV/CF, R&D Systems, Noyal Châtillon sur Seiche, France).

Techniques: Immunostaining, Injection, Saline, Microinjection, Control

Effect of TK receptor inhibitors on the angiogenic activity of FGF2 and VEGF‐A in zebrafish embryos

Journal: Journal of Cellular and Molecular Medicine

Article Title: Fibroblast growth factor 2‐induced angiogenesis in zebrafish: the zebrafish yolk membrane (ZFYM) angiogenesis assay

doi: 10.1111/j.1582-4934.2008.00432.x

Figure Lengend Snippet: Effect of TK receptor inhibitors on the angiogenic activity of FGF2 and VEGF‐A in zebrafish embryos

Article Snippet: Recombinant zebrafish VEGF‐A (zVEGF) and human VEGF‐A were from R&D Systems and Calbiochem Biochemicals (San Diego, CA, USA), respectively.

Techniques: Activity Assay